A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p300/CBP
Type histone modification
Species Mus musculus
Tissue bone
Experiment Method Western blot
Up/Down differential expression
Pro/Anti NA
Funtion Description p300/CBP activation led to H3K27 acetylation to increase expression of senescence-related genes and PPARr in embryonic osteogenic calvarial cells from HFD obese dams.
Regulation Gene PPARr
Year 2018
Pubmed ID 30049822
Title Maternal obesity impairs skeletal development in adult offspring.
Drug NA
Disease obesity
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA