Details
| Name | p53 |
| Type | histone modification |
| Species | Homo sapiens |
| Tissue | MRC5 fibroblasts |
| Experiment Method | Western Blotting,qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | ING2 can act as a cofactor of p300 for p53 acetylation and thereby plays a positive regulatory role during p53-mediated replicative senescence. |
| Regulation Gene | p53 |
| Year | 2005 |
| Pubmed ID | 16024799 |
| Title | ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |