| Name |
p53
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
primary human gingival fibroblasts
|
| Experiment Method |
Luciferase reporter assay,Western Blotting
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
The expression level of HDAC1 protein decreased significantly in HGFs from aged donors compared young donors, but the expression of p53 protein was not notably altered whereas the amount of acetyl-p53 protein increased significantly in HGFs from aged dono
|
| Regulation Gene |
p53
|
| Year |
2004
|
| Pubmed ID |
15130752
|
| Title |
Histone deacetylases, HDAC1 and HSIR2, act as a negative regulator of through p53 in human gingival fibroblast
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|