A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p66Shc promoter
Type histone modification
Species Homo sapiens
Tissue lung
Experiment Method RT-Q-PCR, ChiP
Up/Down Up
Pro/Anti Pro
Funtion Description quantitative chromatin immunoprecipitation showed increased histone H4 acetylation and histone H3 Lys-4 methylation during replicative senescence, while the increased acetylation of histone H3 and H4, as well as increased H3 Lys-4 methylation, was see
Regulation Gene p66Shc
Year 2010
Pubmed ID 20667496
Title Epigenetic enhancement of p66Shc during cellular replicative or premature senescence.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA