A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Rad52
Type histone modification
Species Yeast
Tissue Yeast
Experiment Method PCR,Senescence assay,Southern blot
Up/Down NA
Pro/Anti Pro
Funtion Description In this study, we make use of rad52 separation-of-function mutants to find that multiple Rad52-mediated HDR mechanisms are required to delay senescence, including break-induced replication and sister chromatid recombination. In addition, we show that misr
Regulation Gene H3K56
Year 2016
Pubmed ID 27428329
Title Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Prevent Telomere Attrition-Induced Senescence in Saccharomyces cerevisiae.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA