| Name |
RPs
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
Microarray, qRT-pCR, ChIP-Seq
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Inhibition of SETD8 alone was sufficient to trigger senescence. Under these states, the expression of genes encoding ribosomal proteins (RPs) and ribosomal RNAs as well as the cyclin-dependent kinase (CDK) inhibitor p16INK4A was increased, with a correspo
|
| Regulation Gene |
RPs
|
| Year |
2017
|
| Pubmed ID |
28249161
|
| Title |
The SETD8/PR-Set7 Methyltransferase Functions as a Barrier to Prevent Senescence-Associated Metabolic Remodeling.
|
| Drug |
0
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|