| Name |
SAHF
|
| Type |
histone modification
|
| Species |
Homo sapiens
|
| Tissue |
Human nevus tissues
|
| Experiment Method |
immunofluorescence,ChIP-seq,Western blotting,Mass spectrometry,Chromatin immunoprecipitation,ChIP-qPCR
|
| Up/Down |
Up
|
| Pro/Anti |
NA
|
| Funtion Description |
Rather, we speculate that H4K20me3 plays a role in heterochromatinization and stabilization of the epigenome and genome of pre-malignant, oncogene-expressing senescent cells, thereby suppressing epigenetic and genetic instability and contributing to long-
|
| Regulation Gene |
SAHF
|
| Year |
2016
|
| Pubmed ID |
27457071
|
| Title |
Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|