Details
| Name | ATR |
| Type | gene |
| Species | Mus musculus |
| Tissue | hematopoietic SC |
| Experiment Method | RT-PCR,other |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Although DNA damage is considered a driving force for aging, the nature of the damage that arises endogenously remains unclear. Replicative stress, a source of endogenous DNA damage, is prevented primarily by the ATR kinase. We have developed a mouse mode |
| Regulation Gene | NA |
| Year | 2009 |
| Pubmed ID | 19620979 |
| Title | A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |