A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SET1
Type histone modification
Species Single cell yeast
Tissue NA
Experiment Method qRT-PCR,ChIP-seq
Up/Down differential expression
Pro/Anti Anti
Funtion Description H3K4me3 antagonizes the HIR/Asf1/Rtt106 repressor complex to promote histone gene expression and extend chronological life span.
Regulation Gene Set1
Year 2019
Pubmed ID 30759223
Title Set1-catalyzed H3K4 trimethylation antagonizes the HIR/Asf1/Rtt106 repressor complex to promote histone gene expression and chronological life span.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE115910,GSE81822,GSE72972