Details
| Name | SIRT1 |
| Type | histone modification |
| Species | Homo sapiens |
| Tissue | endothelial |
| Experiment Method | Western blot |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | SIRT1 activity inhibition and SIRT6 gene silencing by small interfering RNA abolished the protective effect of Egt against the high-glucose-induced endothelial senescence. |
| Regulation Gene | SIRT1 |
| Year | 2016 |
| Pubmed ID | 27101740 |
| Title | Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of SIRT1 and SIRT6. |
| Drug | NA |
| Disease | type 2 diabetes |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |