A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT1
Type histone modification
Species Homo sapiens
Tissue NA
Experiment Method Western blotting
Up/Down Down
Pro/Anti NA
Funtion Description Mammalian Sir2 (SIRT1) has also been found to regulate premature cellular senescence induced by the tumor suppressors PML and p53.
Regulation Gene WRN
Year 2008
Pubmed ID 18203716
Title Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA