Details
| Name | SIRT2 |
| Type | histone modification |
| Species | Mus musculus |
| Tissue | cardiac |
| Experiment Method | qPCR |
| Up/Down | differential expression |
| Pro/Anti | NA |
| Funtion Description | SIRT2-deficient mice develop spontaneous pathological cardiac hypertrophy, remodeling, fibrosis, and dysfunction in an age -dependent manner. |
| Regulation Gene | NFAT |
| Year | 2018 |
| Pubmed ID | 29440391 |
| Title | SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |