A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT6
Type histone modification
Species Homo sapiens
Tissue lung
Experiment Method Western blot
Up/Down Up
Pro/Anti Anti
Funtion Description In addition, while the expression levels of histone deacetylases such as HDAC1, SIRT1 and SIRT6 are increased in IMR 90 cells in the presence of scopoletin, the expression levels of histone acetyltransferases are decreased.Furthermore, scopoletin enhances
Regulation Gene p53
Year 2015
Pubmed ID 25837273
Title Scopoletin has a potential activity for anti-aging via autophagy in human lung fibroblasts.
Drug Scopoletin
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA