Details
| Name | SIRT6 |
| Type | histone modification |
| Species | Mus musculus |
| Tissue | renal |
| Experiment Method | ELISA,Western blot |
| Up/Down | differential expression |
| Pro/Anti | Anti |
| Funtion Description | SIRT6 overexpression is sufficient to delay the replicative senescence of WI38 by attenuating NF-kB signaling, while SIRT6 knockdown results in accelerated cell senescence and overactive NF-kB signaling. |
| Regulation Gene | SIRT6 |
| Year | 2016 |
| Pubmed ID | 26940461 |
| Title | Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-kB signaling. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |