Details
| Name | SIRT6 |
| Type | histone modification |
| Species | Homo sapiens |
| Tissue | mesodermal |
| Experiment Method | ChIP-qPCR |
| Up/Down | differential expression |
| Pro/Anti | NA |
| Funtion Description | Our study uncovers a novel function of SIRT6 in maintaining hMSC homeostasis by serving as a NRF2 coactivator, which represents a new layer of regulation of oxidative stress-associated stem cell decay. |
| Regulation Gene | NRF2 |
| Year | 2016 |
| Pubmed ID | 26768768 |
| Title | SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | GSE64642 |