A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SIRT6
Type histone modification
Species Homo sapiens
Tissue NA
Experiment Method Immunofluorescence
Up/Down differential expression
Pro/Anti Pro
Funtion Description Our findings constitute the first identification of a physiological enzymatic activity of SIRT6, and link chromatin regulation by SIRT6 to telomere maintenance and a human premature ageing syndrome.
Regulation Gene SIRT6
Year 2008
Pubmed ID 18337721
Title SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.
Drug NA
Disease premature ageing syndrome
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA