A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SRFBP1
Type histone modification
Species Homo sapiens
Tissue ATCC CRL-1772;mouse hearts
Experiment Method Quantitative RT-PCR, Immunoprecipitation and Western blotting,Immunocytofluorescence
Up/Down NA
Pro/Anti NA
Funtion Description It is therefore very plausible that increased expression of p49/STRAP in late life may alter the status of histone acetylation and impact mitochondrial dynamics and thereby reduce mitochondrial function and cardiac performance during mammalian senescence.
Regulation Gene H4K16
Year 2016
Pubmed ID 27337995
Title Does p49/STRAP, a SRF-binding protein (SRFBP1), modulate cardiac mitochondrial function in aging
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA