A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SUV39H1
Type histone modification
Species Mus musculus
Tissue skin
Experiment Method PCR, ChiP, Western blot
Up/Down Up
Pro/Anti Anti
Funtion Description Altogether, our transgenic mouse model underlines the role of the Suv39h1 HMTase as negative regulator of telomere length and identifies Suv39h1 as an interesting target modulate p53 tumorsuppressor activity and improving resistance to oncogene induced tr
Regulation Gene p53
Year 2015
Pubmed ID 25789788
Title Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice.
Drug 0
Disease Skin carcinogenesis
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA