A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SUV39H1
Type histone modification
Species Homo sapiens
Tissue NA
Experiment Method qRT-PCR
Up/Down Down
Pro/Anti NA
Funtion Description the histone methyltransferase SUV39H1 plays an important role in human B lymphoid differentiation and that expression of SUV39H1. decreases with age in both human and mouse HSC, leading to a global reduction in H3K9 trimethylation and perturbed heterochro
Regulation Gene SUV39H1
Year 2016
Pubmed ID 27304919
Title Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA