A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ZBP-89
Type histone modification
Species Homo sapiens
Tissue NA
Experiment Method RT-PCR,ChIP
Up/Down Down
Pro/Anti Anti
Funtion Description ZBP-89 was able to restrain senescence in NCI-H460 human lung cancer cells, through epigenetically regulating p(16INK4a) expression.
Regulation Gene 16INK4a
Year 2009
Pubmed ID 19583777
Title The transcription factor ZBP-89 suppresses p16 expression through a histone modification mechanism to affect cell senescence.
Drug NA
Disease lung cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA