Details
| Name | Mdm2-a |
| Type | alternative splicing |
| Species | Mus musculus |
| Tissue | subcutaneous tissue |
| Experiment Method | Western blot |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Evidence of p53 activation was shown in the Mdm2-a transgenic MEFs, including p53-dependent growth inhibition and elevated expression of the p53 target protein p21. In addition, MDM2-A increased senescence in a p21-independent manner. In conclusion, unexp |
| Regulation Gene | Mdm2 |
| Year | 2009 |
| Pubmed ID | 19132120 |
| Title | MDM2-A, a common Mdm2 splice variant, causes perinatal lethality, reduced longevity and enhanced senescence |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |