| Name |
Chronos
|
| Type |
lncRNA
|
| Species |
Mus musculus
|
| Tissue |
muscle
|
| Experiment Method |
RNAseq,Quantitative real-time PCR,Luciferase reporter assay,ChIP,Western blot
|
| Up/Down |
Up
|
| Pro/Anti |
NA
|
| Funtion Description |
Here, we identify a long noncoding RNA, named Chronos, whose expression in muscle is positively regulated with advancing age and negatively regulated during Akt1-mediated growth. Inhibition of Chronos induces myofiber hypertrophy both in vitro and in vivo
|
| Regulation Gene |
NA
|
| Year |
2017
|
| Pubmed ID |
28855249
|
| Title |
lncRNA Chronos is an aging-induced inhibitor of muscle hypertrophy
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|