A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Gm14230
Type lncRNA
Species Mus musculus
Tissue cell
Experiment Method RNA-seq,RNA-FISH,western blot,Immunocytochemistry,RIP-qPCR,ChIP
Up/Down Up
Pro/Anti Pro
Funtion Description Gm14230 safeguards cellular juvenescence through recruiting the histone methyltransferase Ezh2 to Tgif2, thereby repressing the functional role of Tgif2 in cellular senescence.
Regulation Gene Tgif2
Year 2019
Pubmed ID 30872457
Title The juvenility-associated long noncoding RNA Gm14230 maintains cellular juvenescence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA