| Name |
LINC00673
|
| Type |
lncRNA
|
| Species |
Homo sapiens
|
| Tissue |
lung
|
| Experiment Method |
RNA FISH,SA-B-Gal senescence assays
|
| Up/Down |
Up
|
| Pro/Anti |
anti
|
| Funtion Description |
We report that loss of LINC00673 is sufficient to trigger cellular senescence, a tumor suppressive mechanism associated with permanent cell cycle arrest, both in lung cancer and normal cells in a p53-dependent manner.
|
| Regulation Gene |
NA
|
| Year |
2018
|
| Pubmed ID |
30499379
|
| Title |
Targeting LINC00673 expression triggers cellular senescence in lung cancer.
|
| Drug |
NA
|
| Disease |
lung cancer,lung adenocarcinoma (ADC)
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|