A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name lncRNA-ES3
Type lncRNA
Species Homo sapiens
Tissue HA-VSMCs
Experiment Method qRT-PCR,SA-B-gal staining,Alizarin Red S staining,Western blot,Luciferase reporter assay,RNA RIP
Up/Down NA
Pro/Anti Pro
Funtion Description lncRNA-ES3 suppressed miR-34c-5p expression by direct interaction.
Regulation Gene miR-34c-5p
Year 2019
Pubmed ID 30654331
Title lncRNA-ES3/miR-34c-6p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs.
Drug NA
Disease Vascular calcification (VC)
Environment Factors high glucose
Circulating NA
Variant NA
High-throughput NA