A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name lncRNA-p21
Type lncRNA
Species Mus musculus
Tissue bone
Experiment Method RT-qPCR,Western blot
Up/Down Up
Pro/Anti Pro
Funtion Description lincRNA-p21 is involved in MSC senescence. Interfering with lincRNA-p21 expression may allow the rejuvenation of aged MSCs by regulation of oxidative stress via the Wnt/B-catenin signaling pathway.
Regulation Gene NA
Year 2017
Pubmed ID 28901439
Title Long noncoding RNAp21 modulates cellular senescence via the Wnt/Bcatenin signaling pathway in mesenchymal stem cells.
Drug H2O2
Disease Myocardial infarction
Environment Factors oxidation
Circulating NA
Variant NA
High-throughput NA