Details
| Name | MIAT |
| Type | lncRNA |
| Species | Homo sapiens |
| Tissue | breast |
| Experiment Method | real-time PCR,Cell senescence-associated beta-galactosidase assay,Western blotting |
| Up/Down | Down |
| Pro/Anti | anti |
| Funtion Description | Unlike P53 positive tumors, Miat expression was upregulated in ER, PR, Her2 positive tumor tissues. Knockdown Miat suppressed breast cancer cell proliferation and caused G1 arrest in cell cycle. Furthermore, downregulation of Miat promoted apoptosis and s |
| Regulation Gene | miR-29a,miR-29c,miR-29b |
| Year | 2018 |
| Pubmed ID | 29345338 |
| Title | MIAT lncRNA is overexpressed in breast cancer and its inhibition triggers senescence and G1 arrest in MCF7 cell line. |
| Drug | NA |
| Disease | lobularbreast cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |