Details
| Name | MIR31HG |
| Type | lncRNA |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | Luciferase reporter assays,Senescence associated b-galactosidase staining,Immunofluorescence,Western blot,qRT-PCR,RNA sequencing,ChIP |
| Up/Down | Down |
| Pro/Anti | anti |
| Funtion Description | We show that MIR31HG interacts with both INK4A and MIR31HG genomic regions and with Polycomb group (PcG) proteins, and that MIR31HG is required for PcG-mediated repression of the INK4A locus. |
| Regulation Gene | p16(INK4A) |
| Year | 2015 |
| Pubmed ID | 25908244 |
| Title | The lncRNA MIR31HG regulates p16(INK4A) expression to modulate senescence. |
| Drug | NA |
| Disease | melanoma |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |