A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name TERRA
Type lncRNA
Species Homo sapiens
Tissue NA
Experiment Method Western blotting,Chromatin immunoprecipitation,quantitative real time PCR
Up/Down Down
Pro/Anti Pro
Funtion Description Levels of TERRA expressed from multiple telomere ends appear elevated at senescence, and expression of an artificial RNA complementary to TERRA (anti-TERRA) binds TERRA in vivo and delays senescence.
Regulation Gene Dot1
Year 2018
Pubmed ID 29649255
Title TERRA and the histone methyltransferase Dot1 cooperate to regulate senescence in budding yeast.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA