Details
| Name | VAD |
| Type | lncRNA |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | FISH,qPCR and western blots,Chromatin immunoprecipitations |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | We show that VAD, a novel antisense vlincRNA strongly induced during senescence, is required for the maintenance of senescence features. VAD modulates chromatin structure in cis and activates gene expression in trans at the INK4 locus, which encodes cell |
| Regulation Gene | NA |
| Year | 2015 |
| Pubmed ID | 25601475 |
| Title | A vlincRNA participates in senescence maintenance by relieving H2AZ-mediated repression at the INK4 locus. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |