A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name OCT4
Type methylation
Species Homo sapiens
Tissue hair follicle
Experiment Method PCR
Up/Down Up
Pro/Anti Pro
Funtion Description The overexpression of p21 abrogated the proliferation and osteogenic differentiation capacity of hHFMSCsOCT4 and promoted cell senescence.
Regulation Gene 4-Oct
Year 2019
Pubmed ID 30646941
Title OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA