A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name 14-3-3sigma
Type methylation
Species Homo sapiens
Tissue cutaneous
Experiment Method PCR
Up/Down Up
Pro/Anti Pro
Funtion Description overexpression of 14-3-3sigma induces senescence of melanoma cells and is involved in melanoma cell senescence under genotoxic stress.
Regulation Gene 14-3-3sigma
Year 2009
Pubmed ID 19642975
Title 14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence.
Drug NA
Disease melanoma
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA