Details
| Name | 5a-reductase-1 promoter |
| Type | methylation |
| Species | Rat Rattus |
| Tissue | Female rats strain |
| Experiment Method | qPCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | To elucidate the effects of environmental enrichment, a subgroup of middle-aged rats exposed to sensory and social stimulation for 105 days was compared to rats housed under standard laboratory conditions. Aging decreased the transcription of neurosteroid |
| Regulation Gene | 5a-reductase-1 |
| Year | 2015 |
| Pubmed ID | 26021641 |
| Title | Environmental enrichment attenuates the age-related decline in the mRNA expression of steroidogenic enzymes and reduces the methylation state of the steroid 5a-reductase type 1 gene in the rat hippocampus |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |