Details
| Name | ABCG1 promoter |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | heart |
| Experiment Method | PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Our data indicates that promoter DNA hypermethylation of the ABCG1 and GALNT2 genes, but not the HMGCR gene, is associated with an increased risk of CHD.CHD, smoking and aging are likely to be the important factors influencing DNA hypermethylation. |
| Regulation Gene | ABCG1, GALNT2 |
| Year | 2014 |
| Pubmed ID | 25084356 |
| Title | A preliminary study of the relationship between promoter methylation of the ABCG1, GALNT2 and HMGCR genes and coronary heart disease. |
| Drug | 0 |
| Disease | coronary heart disease |
| Environment Factors | smoking |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |