| Name |
amyloid precursor protein gene
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
Brains were obtained within 12 h after death from 10 subjects six males and four females, aged 35-90 years
|
| Experiment Method |
PCR;bisulfite-treat
|
| Up/Down |
Down
|
| Pro/Anti |
NA
|
| Funtion Description |
Cytosines at -207, -204, -200, and -182 are frequently methylated, and the frequency of methylcytosine in these locations was significantly higher in cases 70 years old.These cytosines constituted one of the 9-bp-long GC-rich e
|
| Regulation Gene |
the amyloid precursor protein gene
|
| Year |
1999
|
| Pubmed ID |
10407177
|
| Title |
Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortex.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|