A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BRAF V600E
Type methylation
Species Mus musculus
Tissue colon-derived organoids
Experiment Method qMSP
Up/Down Up
Pro/Anti NA
Funtion Description promoter hypermethylation spontaneously arises in cells mimicking the human aging-like phenotype.
Regulation Gene BrafV600E
Year 2019
Pubmed ID 30753828
Title Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE114801, GSE114801,GSE114801