A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Bcl2
Type gene
Species Mus musculus
Tissue mice strains
Experiment Method immunohistochemistry
Up/Down Up
Pro/Anti Anti
Funtion Description Overexpression of the proto-oncogene bcl-2 delayed onset of motor neuron disease and prolonged survival in transgenic mice expressing the FALS-linked mutation in which glycine is substituted by alanine at position 93. It did not, however, alter the durati
Regulation Gene NA
Year 1997
Pubmed ID 9228005
Title Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA