A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CD27
Type methylation
Species Homo sapiens
Tissue Peripheral blood mononuclear cells
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description By contrast, older individuals showed increased methylation and decreased expression of the chemokine receptor CCR7 responsible for T cell homing to lymph nodes and activation, the membrane surface marker CD27 involved in T cell expansion and induction of
Regulation Gene CD27
Year 2015
Pubmed ID 26286994
Title Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA