A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name cg00666422
Type methylation
Species Homo sapiens
Tissue blood
Experiment Method SNP genotyping,bisulfite-sequencing
Up/Down NA
Pro/Anti NA
Funtion Description The leptin gene (LEP) plays a regulatory role in satiety, inflammation, and allergy. Prior findings linking leptin to asthma motivated us to investigate whether DNA methylation (DNA-M) of CpG (cytosine-phosphate-guanine) sites in concert with single nucle
Regulation Gene LEP
Year 2016
Pubmed ID 27186323
Title DNA methylation and genetic polymorphisms of the Leptin gene interact to influence lung function outcomes and asthma at 18 years of age.
Drug NA
Disease asthma
Environment Factors NA
Circulating 1
Variant rs11763517
High-throughput NA