A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BCL6
Type gene
Species Mus musculus
Tissue primary Balb/c MEFs
Experiment Method Western blot
Up/Down NA
Pro/Anti Anti
Funtion Description We show that BCL6 expression also dramatically extends the replicative lifespan of primary human B cells in culture and induces cyclin D1 expression, indicating that BCL6 has a similar activity in lymphoid cells. Our results suggest that BCL6 contributes
Regulation Gene NA
Year 2002
Pubmed ID 11914273
Title A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19ARF-p53 signaling
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA