A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name cg11314684
Type methylation
Species Homo sapiens
Tissue blood
Experiment Method Human Methylation 450 Beadchip array
Up/Down Up
Pro/Anti Anti
Funtion Description Telomere length (TL) is associated with an increased risk of aging-related diseases. After correction for multiple testing, we successfully confirmed that seven out of 151 smoking-related CpG sites were associated with TL (FDR <0.05).
Regulation Gene AKT3, POLK, HNRNPA1, EDC3
Year 2016
Pubmed ID 27832427
Title DNA methylation changes in response to active smoking exposure are associated with leukocyte telomere length among older adults.
Drug 0
Disease NA
Environment Factors smoking
Circulating 1
Variant NA
High-throughput NA