| Name |
C-MYC
|
| Type |
methylation
|
| Species |
Mus musculus
|
| Tissue |
liver
|
| Experiment Method |
Global methylation, qRT-PCR, Western blot, Methylation-sensitive high-resolution melting PCR
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Folate deficiency with age resulted in the up-regulation of proto-oncogenes (C-MYC and C-JUN) and cell cycle regulator gene Cyclin E as a result of promoter hypomethylation.
|
| Regulation Gene |
C-MYC
|
| Year |
2017
|
| Pubmed ID |
29220669
|
| Title |
Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation.
|
| Drug |
0
|
| Disease |
NA
|
| Environment Factors |
Folate deficiency
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|