A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name C-MYC
Type methylation
Species Mus musculus
Tissue spleen and liver
Experiment Method Southern blot analysis;Northern blot analysis
Up/Down Up/Down
Pro/Anti NA
Funtion Description It was flanked by partially methylated regions, where age-dependent changes as well as tissue specificity were observed. In the spleen, age-related hypomethylation was observed at both the 3' and 5' sides of the domain. In contrast, hypermethylation was f
Regulation Gene c-myc
Year 1989
Pubmed ID 2911270
Title Age-associated changes in DNA methylation and mRNA level of the c-myc gene in spleen and liver of mice
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA