A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name COX1
Type methylation
Species Homo sapiens
Tissue heart
Experiment Method qRT-pCR
Up/Down Down
Pro/Anti Anti
Funtion Description The mitochondrial COX1 gene, which encodes the main subunit of the cytochrome c oxidase complex and contains the differentially methylated CpG island 4, was upregulated in MSCs in parallel with the onset of senescence.As the degree of mtDNA methylation at
Regulation Gene COX1
Year 2017
Pubmed ID 28484495
Title Mitochondrial DNA Hypomethylation Is a Biomarker Associated with Induced Senescence in Human Fetal Heart Mesenchymal Stem Cells.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA