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Details


Name CPEB1 promoter
Type methylation
Species Homo sapiens
Tissue brain
Experiment Method PCR, ChiP, Luciferase reporter assay, Western blot
Up/Down Up
Pro/Anti Anti
Funtion Description the mRNA translation-related gene cytoplasmic polyadenylation element-binding protein 1 (CPEB1) is hypomethylated and overexpressed in glioma cells and tissues. The knockdown of CPEB1 reduced cell senescence by regulating the expression or distribution
Regulation Gene CPEB1, p53
Year 2013
Pubmed ID 23788032
Title CPEB1, a histone-modified hypomethylated gene, is regulated by miR-101 and involved in cell senescence in glioma.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA