A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BLM
Type gene
Species Homo sapiens
Tissue blood
Experiment Method PCR,other
Up/Down Down
Pro/Anti Pro
Funtion Description The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disab
Regulation Gene NA
Year 2018
Pubmed ID 29449545
Title Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA