| Name |
CREG1 promoter
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
Bone
|
| Experiment Method |
PCR, Flow cytometry assay, Western blot
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
During the spontaneous immortalization of Li-Fraumeni Syndrome (LFS) fibroblasts, we found that CREG1 (Cellular Repressor of E1A-stimulated Genes 1) expression was decreased during immortalization and increased in senescence. Moreover, we found that re
|
| Regulation Gene |
CREG1, p16 (INK4a), cyclin A, cyclin B
|
| Year |
2011
|
| Pubmed ID |
21263217
|
| Title |
CREG1 enhances p16(INK4a) -induced cellular senescence.
|
| Drug |
5-aza-dC
|
| Disease |
osteosarcoma and fibrosarcoma
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|