A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Cx26 promoter
Type methylation
Species Mus musculus
Tissue ear
Experiment Method qRT-PCR, Immunofluorescence
Up/Down Up
Pro/Anti Pro
Funtion Description The common deletion (CD) incidence increased in the inner ear of aging rats induced by D-gal. The Cx26 expression level decreased in the inner ear of aging rats induced by D-gal. Bisulfite sequencing PCR indicated an increase of CpG site methylation of th
Regulation Gene Cx26
Year 2014
Pubmed ID 25159847
Title Reduced expression of Connexin26 and its DNA promoter hypermethylation in the inner ear of mimetic aging rats induced by d-galactose.
Drug D-gal
Disease common deletion (CD)
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA