A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type methylation
Species Caenorhabditis elegans
Tissue NA
Experiment Method RT-qPCR
Up/Down differential expression
Pro/Anti NA
Funtion Description chromatic repression mediated by tissue-specific H3K36 dimethyltransferase might be detrimental to lifespan and may have implications in human age-related diseases.
Regulation Gene daf-16a
Year 2018
Pubmed ID 29514099
Title Muscle-Specific Histone H3K36 Dimethyltransferase SET-18 Shortens Lifespan of Caenorhabditis elegans by Repressing daf-16a Expression.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE49721,GSE28776