A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DG
Type methylation
Species Mus musculus
Tissue brain
Experiment Method Immunohistochemistry
Up/Down Up
Pro/Anti Pro
Funtion Description In the 3xTg-AD mice, an age-related increase in DNA methylation was found in the DG and CA1-2. In the J20 mouse model, an age-related decrease in DNA methylation was found in the dentate gyrus(DG) and a decrease in the ratio between DNA methylation and hy
Regulation Gene DG
Year 2018
Pubmed ID 29113959
Title Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
Drug 0
Disease Alzheimer's disease
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA